博导
白丁
姓名:白丁
职称:教授
所在学系:口腔正畸学系
研究生导师类别:博导/硕导
电子邮箱:baiding@scu.edu.cn
办公地址:四川省成都市人民南路三段14号华西口腔医院4楼一诊室
研究方向:口腔正畸的生物学与生物力学
个人简介:
1982-1988,华西医科大学口腔医学院,获学士学位。
1988-1993,华西医科大学口腔医学院正畸科,获博士学位。
1993-至今,四川大学华西口腔医学院正畸学系工作,历任助教、副教授、教授,博士生导师。
其它学术任职有:中华口腔医学会正畸专业委员会副主任委员、四川省口腔医学会正畸专委会主任委员、四川省口腔医学会美学专委会副主任委员、四川省医学会口腔医学专委会常委、四川省医学会医学美学与美容专委会常委、四川省口腔医学会装备专委会常委,四川省卫生厅学术技术带头人,Member of the Edward H. Angle Society of Orthodontists,Associated Editor of “Progress in Orthodontics”,《华西口腔医学杂志》、《中华口腔正畸学杂志》、《中国实用口腔科杂志》编委等职务。
获四川省科技进步一等奖(排名第一)等部省级科研奖励多项。
研究领域:
承担国家自然科学基金面上项目7项、科技部项目、部省级科研课题多项,在正畸牙移动的牙周组织生物学基础、髁突软骨成骨转化机制、数字化正畸等方面有较多研究。
1. 负责人:应力微环境下YAP-Sox2转录轴调控髁突软骨细胞成骨转化的机制。国家自然科学基金。2019-2022。
2. 负责人:系统性数字化正畸诊疗技术国际培训班,国家科技部2018年度发展中国家技术培训班项目, 2018。
3. 负责人:应力微环境下YAP/TAZ介导牙周膜肌成纤维细胞的分化机制。国家自然科学基金。
4. 负责人:口腔数字化诊疗技术与装置的研发。四川省科技支撑计划。250万元。
论文/著作:
发表科研论文200 余篇,SCI收录80 余篇,近三年发表论文:
1. Chaoran Xue, Hui Xu, Yongwen Guo, Li Xu, Yogyata Dhami, Hongzhe Wang, Zhongyu Liu, Jianbin Ma, Ding Bai*. Accurate bracket placement using a computer-aided design and computer-aided manufacturing–guided bonding device: An in vivo study. AJODO, 2020, 157(2): 269-277.
2. Chen T, Liu Z, Xue C, Tian W, Bai D*, Chen YP*. Association of Dysplastic Coronoid Process with Long-Face Morphology. J Dent Res. 2019 Dec 11:22034519892551. doi: 10.1177/0022034519892551.
3. Liu Z, Chen T, Bai D, Tian W, Chen Y*. Smad7 Regulates Dental Epithelial Proliferation during Tooth Development. J Dent Res. 2019, Nov; 98(12): 1376-1385. doi: 10.1177/0022034519872487.
4. Li J, Xue J, Jing Y, Wang M, Shu R, Xu H, Xue C, Feng J, Wang P, Bai D*. SOST Deficiency Aggravates Osteoarthritis in Mice by Promoting Sclerosis of Subchondral Bone. Biomed Res Int. 2019 Nov 11;2019:7623562. doi: 10.1155/2019/7623562. eCollection 2019.
5. Feng J, Luo M, Ma J, Tian Y, Han X, Bai D*. The treatment modalities of masticatory muscle pain a network meta-analysis. Medicine. 2019 Nov;98(46):e17934. doi: 10.1097/MD.0000000000017934..
6. Wang M, Li S, Zhang P*, Wang Y, Wang C, Bai D*, Jiang X*. EMP2 acts as a suppressor of melanoma and is negatively regulated by mTOR-mediated autophagy. Cancer. 2019 Jun 9;10(16):3582-3592. doi: 10.7150/jca.30342. eCollection 2019.
7. Wen Y, Yang H, Wu J*, Wang A, Chen X, Hu S, Zhang Y, Bai D*, Jin Z*. COL4A2 in the tissue-specific extracellular matrix plays important role on osteogenic differentiation of periodontal ligament stem cells. Theranostics. 2019 May 31;9(15):4265-4286. doi: 10.7150/thno.35914. eCollection 2019.
8. Xu Y, Lv C, Zhang J, Li Y, Li T, Zhang C, Chen J, Bai D, Yin X, Zou S. Intermittent parathyroid hormone promotes cementogenesis in a PKA- and ERK1/2-dependent manner. J Periodontol. 2019 Apr 26. doi:
9. He Y, Xu H, Xiang Z, Yu H, Xu L, Guo Y, Tian Y, Shu R, Yang X, Xue C, Zhao M, He Y, Han X, Bai D*. YAP regulates periodontal ligament cell differentiation into myofibroblast interacted with RhoA/ROCK pathway. J Cell Physiol. 2019 Apr;234(4):5086-5096. doi: 10.1002/jcp.27312.
10. Zhao M, Dai W, Wang H, Xue C, Feng J, He Y, Wang P, Li S, Bai D, Shu R. Periodontal ligament fibroblasts regulate osteoblasts by exosome secretion induced by inflammatory stimuli. Arch Oral Biol. 2019 Jun 5;105:27-34. doi: 10.1016/j.archoralbio.2019.06.002
11. Du W, Chen G, Bai D, Xue C, Fei W, Luo E. Treatment of skeletal open bite using a navigation system: CAD/CAM osteotomy and drilling guides combined with pre-bent titanium plates. Int J Oral Maxillofac Surg. 2019 Apr;48(4):502-510. doi: 10.1016/j.ijom.2018.08.012. Epub 2018 Sep 20.
12. Xue C, Xu H, Tian Y, Yang X, Luo E, Bai D*. Precise control of maxillary multidirectional movement in Le Fort I osteotomy using a surgical guiding device. Br J Oral Maxillofac Surg. 2018 Nov; 56(9): 797-804.. doi: 10.1016/j.bjoms.2018.08.013.
13. Xue C, Tian Y, Wang L, Yang X, Luo E, Bai D*. Surgical guide and CAD/CAM prebent titanium plate for sagittal split ramus osteotomy in the correction of mandibular prognathism. Br J Oral Maxillofac Surg. 2018 Sep; 56(7):586-593. doi: 10.1016/j.bjoms.2018.06.007. Epub 2018 Jul 2.
14. Zhou B, Xia X, Wang P, Chen S, Yu C, Huang R, Zhang R, Wang Y, Lu L, Yuan F, Tian Y, Fan Y, Zhang X, Shu Y, Zhang S, Bai D, Wu L, Xu H, Yang L. Induction and Amelioration of Methotrexate-Induced Gastrointestinal Toxicity are Related to Immune Response and Gut Microbiota. EBioMedicine. 2018 Jul;33:122-133. doi: 10.1016/j.ebiom.2018.06.029. Epub 2018 Jul 2.王沛琪
15. Guo Y, Guo W, Chen J, Chen G, Tian W*, Bai D*. Are Hertwig's epithelial root sheath cells necessary for periodontal formation by dental follicle cells? Arch Oral Biol. 2018 Oct; 94:1-9. doi: 10.1016/j.archoralbio.2018.06.014. Epub 2018 Jun 18.
16. Wu F, Li S, Zhang N, Huang W, Li X*, Wang M, Bai D*, Han B*. Hispidulin alleviates high-glucose-induced podocyte injury by regulating protective autophagy. Biomed Pharmacother. 2018 Aug; 104:307-314. doi: 10.1016/j.biopha.2018.05.017. Epub 2018 May 15.
17. Guo Y, Guo W, Chen J, Tian Y, Chen G, Tian W*, Bai D*. Comparative study on differentiation of cervical-loop cells and Hertwig's epithelial root sheath cells under the induction of dental follicle cells in rat. Sci Rep. 2018 Apr 25; 8(1):6546. doi: 10.1038/s41598-018-24973-0.
18. Zhao X., Deng P., Iglesias-Bartolome R., Amornphimoltham P., Steffen J. D., Jin Y., Molinolo A., Ovejero D., Yuan Q., Chen Q., Han X., Bai D., Taylor S. S., Collins T. M., Yang Y., Gutkind J. S. Expression of an active Gαs mutant in skeletal stem cells is sufficient and necessary for fibrous dysplasia initiation and maintenance. Proc Natl Acad Sci U S A. 2018 Jan 16; 115(3):E428-E437. doi: 10.1073/pnas.1713710115. Epub 2017 Dec 27.. IF = 9.7.
19. Xianrui Yang, Chaoran Xue, Yiruo He, Mengyuan Zhao, Mengqi Luo, Peiqi Wang, Ding Bai*. Transversal changes, space closure, and efficienvy of conventional and self-ligating appliances: A quantitative systematic review. J Orofac Orthop. 2018 Jan; 79(1):1-10. doi: 10.1007/s00056-017-0110-4. Epub 2017 Nov 3.
20. Xu H, He Y, Feng JQ, Shu R, Liu Z, Li J, Wang Y, Xu Y, Zeng H, Xu X, Xiang Z, Xue C, Bai D*, Han X*. Wnt3α and transforming growth factor-β induce myofibroblast differentiation from periodontal ligament cells via different pathways. Exp Cell Res. 2017 Apr 15; 353(2):55-62. doi: 10.1016/j.yexcr.2016.12.026. Epub 2017 Feb 20.
21. Yang X, He Y, Chen T, Zhao M, Yan Y, Wang H, Bai D*. Differences between active and passive self-ligating brackets for orthodontic treatment : Systematic review and meta-analysis based on randomized clinical trials. J Orofac Orthop. 2017 Mar; 78(2):121-128. doi: 10.1007/s00056-016-0059-8. Epub 2017 Feb 21. Review.
22. Huang Y, Yan Y, Cao J, Xie B, Xiao X, Luo M, Bai D, Han X*. Obeservations on association between third molar agenesis and craniofacial morphology. J Orofac Orthop. 2017 Nov; 78(6):504-510. doi: 10.1007/s00056-017-0109-x. Epub 2017 Oct 27.
23. He Y, Zhang M, Huang AY, Cui Y, Bai D, Warman ML. Confocal imaging of mouse mandibular condyle cartilage. Sci Rep. 2017 Mar 7;7:43848. doi: 10.1038/srep43848.
24. Rui Shu, Ding Bai, Tzongjen Sheu, Yao He, Xianrui Yang, Chaoran Xue, Yiruo He, Mengyuan Zhao, Xianglong Han*. Sclerostin Promotes Bone Remodeling in the Process of Tooth Movement. PLoS One. 2017 Jan 12;12(1):e0167312. doi: 10.1371/journal.pone.0167312. eCollection 2017.
25. Rui Shu, Dongqing Ai, Ding Bai, Jinlin Song, Mengyuan Zhao, Xianglong Han*. The effects of SOST on implant osseointegration in ovariectomy osteoporotic mice. Archives of Oral Biology, 2017. 74: 82–91.
专著
1. 副主编,王林主编白丁李巍然金作林房兵严斌副主编,《口腔正畸形就医指南》,人民卫生出版社,2019,2
2. 主编,赵志河,白丁,《口腔正畸科诊疗与操作常规》,人民卫生出版社,2018.11。
3. 参编,《口腔生物力学》,2018
4. 主编,白丁,赵志河,《口腔正畸策略、控制与技巧》,人民卫生出版社,2015.10,133万字。
5. 主译,李煌,白丁,《CBCT在口腔正畸中的临床应用》,人民军医出版社,2015.10。
6. 副主译,《正畸临床病例解析》,辽宁科学技术出版社,2013。
7. 副主编,《口腔正畸学----基础,技术与临床》,人民卫生出版社,2012。
8. 副主编,《牙颌面畸形功能矫形》,科学技术文献出版社,2011。
9. 副主编,《美容牙科学》,人民卫生出版社。卫生部“十一五”规划教材,2010。
10. 副主编,《当代实用口腔正畸技术与理论》,科学技术文献出版社,2010
11. 参编,《中华口腔科学(第二版)》,人民卫生出版社,2009,p2186-2195。
12. 主编,《正畸矫治方案设计》,人民卫生出版社。2008。
13. 副主编,《美容口腔学》,人民军医出版社,2004,p249-282。
14. 参编,《中华口腔科学》,人民卫生出版社,2001,p2186-2195。
15. 参编,《功能矫形学》,人民卫生出版社,2000,p239-258。