姓名：邹淑娟

职称：教授

所在学系：口腔正畸学系

研究生导师类别：博导

电子邮箱：shujuanzou@aliyun.com

办公地址：四川省成都市人民南路三段14号华西口腔医院4楼1诊室

研究方向：牙颌面畸形矫治机理的研究

个人简介

1. 教育经历

2002/09-2005/06,四川大学，华西口腔医学院正畸系，博士

1989/09-1992/06：华西医科大学,华西口腔医学院，硕士

1981/09-1987/06：华西医科大学，口腔医学院，本科

2. 研究工作经历

2007/07-至今：四川大学华西口腔医学院 教授，博士生导师

2002/07-2007/07：四川大学华西口腔医学院 副主任医师，硕士生导师

2001/03-2002/01：荷兰阿姆斯特丹大学牙科中心ACTA 研修

1995/07-2002/07：四川大学口腔医学院 讲师

1992/07-1995/07：华西医科大学口腔医学院 助教/住院医师

1987/07-1989/08：贵阳医学院 助教/住院医师

研究领域：

国家自然科学基金负责人5项

1. 甲状旁腺激素对正畸牙移动所致牙根吸收的影响及其分子机制研究

2.  应力刺激下牙根吸收和修复过程中相关microRNAs的调控作用和机制研究

3. TGF-β/Smad信号传导通路对骨缝牵张成骨分子调控的研究

4. Ras/Raf/MEK/ERK蛋白级联反应对骨缝牵张成骨的调控

5. 张应力调控骨缝间充质干细胞骨向分化的研究

高等学校博士学科点专项科研基金负责人1项：

1. Lactoferrin 在骨缝牵张成骨中的作用及机制的研究

四川省科技厅项目4项

1. Wnt/β-catenin信号通路对应力刺激下牙根吸收与修复过程的调控机制研究

2. 中国西部地区青少年牙龄与骨龄相关性调查研究

3. 基因修饰技术促进骨缝牵张成骨的研究

4. 骨生长因子对颅面骨缝牵张的成骨调控

论文/著作：

近期发表的论文

1. M.K.Ge，W.L.He，J.Chen，C.Wen，X.Yin，Z.A.Hu，Z.P.Liu，S.J.Zou Efficacy of low-level laser therapy for accelerating tooth movement during orthodontic treatment: a systematic review and meta-analysis. Lasers Med Sci. 2015 Jul;30(5):1609-18. (通讯作者)

2. Peipei Duan; Wenwen Qu; Shujuan Zou; Yangxi Chec; Hui Lan; Mauro Farella; Li Mei Influence of fixed orthodontic treatment on the menstrual cycle of adult females: A prospective longitudinal study. Angle Orthod. 2015 Aug 19. DOI: 10.2319/121814-922.1(通讯作者)

3. Zhiai Hu，Xing Yin，Jing Liao，Chenchen Zhou，Zhenjin Yang，Shujuan Zou The effect of teeth extraction for orthodontic treatment on the upper airway: a systematic review. Sleep Breath. 2015 May;19(2):441-51.(通讯作者)

4. Peipei Duan,Feng Cai, Yongting Luo, Yangxi Chen and Shujuan Zou Long-term chemiluminescence signal is produced in the course of luminol oxidation catalyzed by enhancer-independent peroxidase purified from Jatropha curcas leaves.Luminescence. 2015 Sep;30(6):818-22.(通讯作者)

5. Zeping Liu, Xing Yin, Qingsong Ye, Wulin He, Mengke Ge, Xiaofu Zhou, Jing Hu and Shujuan Zou Periodontal regeneration with stem cells-seeded collagen-hydroxyapatite scaffold。2016, Vol. 31(1) 121–131(通讯作者)

6. Chenchen Zhou, Brian E. Grottkau, and Shujuan Zou Regulators of Stem Cells Proliferation in Tissue Regeneration Current Stem Cell Research & Therap 2016;11(3):177-87(通讯作者)

7. Y. Cheng，J. W. Chen， M. K. Ge， Z. Y. Zhou， X. Yin， S. J. Zou Efficacy of adjunctive laser in non-surgical periodontal treatment: a systematic review and meta-analysis。Lasers Med Sci 2016 Jan;31(1):151-63.(通讯作者)

8. Jing Liao , Zeyuan Zhou , Li Huang , Yuyu Li , Jingtao Li , Shujuan Zou 17b-estradiol regulates the differentiation of cementoblasts via Notch signaling cascade。Biochemical and Biophysical Research Communications 477 (2016) 109-114。(通讯作者)

9. Fan Li, Guifeng Li, Haikun Hu, Renkai Liu Jianwei Chen,c and Shujuan Zou Effect of parathyroid hormone on experimental tooth movement in rat Am J Orthod Dentofacial Orthop 2013;144:523-32(通讯作者)

10. Haikun Hu, Jianwei Chen, Jing Guo, Fan Li, Zeping Liu, Shushu He, and Shujuan Zou Distalization of the mandibular dentition of an adult with a skeletal Class III malocclusion American Journal of Orthodontics & Dentofacial Orthopedics 2012，142(6)：854-862(通讯作者)

11. W. L. He， C. J. Li， Z. P. Liu， J. F. Sun， Z. A. Hu， X. Yin， S. J. Zou Efficacy of low-level laser therapy in the management of orthodontic pain: a systematic review and meta-analysis Lasers Med Sci 2012 Sep 22(通讯作者)

12. F. Li, H. K. Hu, J. W. Chen, Z. P. Liu, G. F. Li, S. S. He, S. J. Zou , and Q. S. Ye Comparison of anchorage capacity between implant and headgear during anterior segment retraction。 Angle Orthod 2011;81:915–922(通讯作者)

13. ZP Liu, CJ Li, HK HU, JW Chen, SJ Zou. Efficacy of short-term chincup therapy for mandibular growth retardation in Class III malocclusion. Angle Orthod. 2011 Jan;81(1):164-70 (通讯作者)

14. Liu RK, Wamalwa P, Lu DW, Li CH, Hu HK, Zou S .Soft-tissue characteristics of operated unilateral complete cleft lip and palate patients in mixed dentition. J Craniofac Surg. 2011 Jul;22(4):1275-9. (通讯作者)

15. Liu R, Xiaoqing M, Wamalwa P, Zou SJ*. Nonsurgical treatment of an adult patient with bilateral posterior crossbite. Am J Orthod Dentofacial Orthop 2011;140:106-14. (通讯作者)

16. Liu R, Lu D, Wamalwa P, Li C, Hu H, Zou S *. Craniofacial morphology characteristics of operated unilateral complete cleft lip and palate patients in mixed dentition.Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2011 Dec;112(6):e16-25. (通讯作者)

17. Guo J, Li C, Zhang Q, Wu G, Deacon SA, Chen J, Hu H, Zou S *, Ye Q Secondary bone grafting for alveolar cleft in children with cleft lip or cleft palate. Cochrane Database Syst Rev. 2011 Jun 15;(6):CD008050. Review. (通讯作者)

18. Liu RK, Li CH, Zou SJ*. Reducing Scar Formation after Lip Repair by Injecting Botulinum Toxin. Plastic and Reconstructive Surgery 2010, 125(5):1573-1574

19. Jianwei Chen, Jing Guo, Jing Zhou, Renkai Liu, Tingting Chen, Shujuan Zou *. Assessment of dental maturity of western Chinese children using Demirjian‘s method. Forensic Sci Int. 2010 ,74:99-119(通讯作者)

20. Chen J, Hu H, Guo J, Liu Z, Liu R, Li F, Zou S* .Correlation between dental maturity and cervical maturity Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2010,110(6):777-83

21. Qi-feng Zhang, Jing Guo, Gui-feng Li, Shujuan Zou * ,Zhihe Zhao. A potential therapeutic method for conductive hearing loss in growing children-orthodontic expansion treatment. Med Hypotheses. 2010 ;74(1):99-101. (通讯作者)

22. Qingran Shen, Songsong Zhu, Jing Hu, Ning Geng, Shujuan Zou . Recombinant Human Bone Morphogenetic Protein-4(BMP-4) Stimulated Cell Differentiation and Bone Formation Within the Expanding Calvarial Suture in Rats. The Journal of Craniofacial Surgery 2009 20(5)：1561-1565 (通讯作者)

23. Jiang X, Zou S, Ye B, Zhu S, Liu Y, Hu J. bFGF-Modified BMMSCs Enhance Bone Regeneration Following Distraction Osteogenesis in Rabbits. Bone, 2010 ;46(4):1156-61.

24. Qi MC, Zou SJ, Han LC, Zhou HX, Hu J. Expression of bone-related genes in bone marrow MSCs after mechanical strain: implication of distraction osteogenesis. Int J Oral Sci 2009; 1(3): 145-153.

25. Zhou H, Zou S, Lan Y, Fei W, Jiang R, Hu J. Smad7 modulates TGF-beta signaling during cranial suture development to maintain suture patency. J Bone Miner Res 2013 Aug 19. doi: 10.1002/jbmr.2066. [Epub ahead of print]

专 著

1. 主编陈扬熙，副主编：赵志河、白丁、赖文莉、邹淑娟，《口腔正畸学—基础、技术与临床》， 人民卫生出版社。154.9万字，2012

2. 主编罗颂椒，副主编：陈扬熙、赵美英、段玉贵、赵志河、白丁、邹淑娟，《当代实用口腔正畸技术与理论》，科学技术文献出版社。66.5万字，2010

学术奖励情况：

1. 《颅颌面牵张成骨的应用基础研究》,教育部科技进步一等奖，2007年 排名第四

2. 下颌牵张对血管和颞下颌关节影响的研究 四川省科学技术奖三等奖2006排名第三