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硕导

李精韬

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姓名:李精韬

职称:副教授

所在学系:口腔颌面外科学系

研究生导师类别:硕导

电子邮箱:lijingtao86@163.com

联系电话:028-85501462

办公地址:四川省成都市人民南路三段14号华西口腔医院13楼

研究方向:颅颌面先天畸形与缺损修复

个人简介:

李精韬,口腔医学博士,四川大学华西口腔医院口腔颌面外科副教授,硕士研究生导师。美国斯坦福大学整形外科学博士后,美国德州儿童医院整形外科访问学者,美国UCSF牙学院访问学者,中华口腔医学会唇腭裂专委会青年委员、工作秘书,中华整形美容协会-精准与数字医学分会理事。四川大学优秀青年学者。主持国家自然科学基金1项,四川省科技支撑计划1向,参与国家自然科学基金4项、美国国立卫生研究院基金1项、美国加州再生医学研究院基金1项。发表SCI论文40余篇,其中第一及通讯作者28篇。参编《Comprehensive Cleft Care, 2nd edition》《Plastic Surgery》等国际权威论著。副主编《唇腭裂手术治疗学》。获2017年华夏医学科技进步奖。

研究领域:

1. 颌面肌肉再生与纤维化调控机制

2. 唇腭裂骨性畸形数字化整复

论文/著作:

参编著作:

1. Jingtao Li, R Chase Ransom, Jill A Helms. Embryology for orofacial clefting. In: Losee JE, Kirschner RE, editors. Comprehensive cleft care. 2nd edition. CRC Press. ISBN 9781482240894, 2015.12.1

2. Jingtao Li, Jill A. Helms. Embryogenesis of craniofacial complex. In Neligan. Plastic Surgery Vol III: Craniofacial, Head & Neck Surgery and Pediatric Plastic Surgery 4th edition, Elsevier,2017.9.

3. 李精韬(副主编,编委),唇腭裂手术治疗,人民军医出版社,ISBN: 9787509181768,2015.2

论文发表

1. Jingtao Li, Xing Yin, Lan Huang, Syvian Mouraret, John B. Brunski, L. Cordova, Benjamin Salmon, Jill A. Helms. Relationships among Bone Quality, Implant Osseointegration, and Wnt Signaling. Journal of Dental Research. 2017 Jul;96(7):822-831.

2. Jingtao Li, Chelsey A. Johnson, Andrew A. Smith, John B. Brunski, Jill A. Helms. Linking suckling biomechanics to the development of the palate [J]. Scientific reports, 2016, Feb 4: 6, 20419.

3. Jingtao Li, Chelsey A. Johnson, Andrew A. Smith, Benjamin Salmon, Bing Shi, John B. Brunski, Jill A. Helms. Disrupting the intrinsic growth potential of a suture contributes to midfacial hypoplasia. Bone, 2015, 81(12): 186-95.

4. Jingtao Li, Chelsey A. Johnson, Andrew A. Smith, Bing Shi, John B. Brunski, Jill A Helms. Molecular mechanisms underlying skeletal growth arrest by cutaneous scarring. Bone, 2014, 66(9): 223-231.

5. Jingtao Li, Bing Shi, Kun Liu, Qian Zheng, Yan Wang, Sheng Li. A photogrammetry study of the effects of alveolar bone graft on nose symmetry among unilateral cleft patients. Journal of Plastic Reconstructive and Aesthetic Surgery. 2011, 64 (11): 1436-1443.

6. Jingtao Li, Bing Shi, Kun Liu, Qian Zheng. A preliminary study on the hard-soft tissue relationships among unoperated secondary unilateral cleft nose deformities. Oral Surgery Oral Medicine Oral Pathology Oral Radiology. 2012, 113(3): 300-307.

7. Jingtao Li, Kun Liu, Jiayu Shi, Yan Wang, Qian Zheng, Bing Shi. Commissural symmetry in unilateral transverse facial cleft patients: An anthropometric study. Journal of Oral and Maxillofacial Surgery. 2012, 79(9): 2184-2190.

8. Wang Y, Li J(共同一作), Xu Y, Huang N, Shi B, Li J. Accuracy of virtual surgical planning-assisted management for maxillary hypoplasia in adult patients with cleft lip and palate. J Plast Reconstr Aesthet Surg,2019.7, S1748-6815(19)30336-5.

9. Tao Chen, Jingtao Li (共同一作), Luis A. Cordova, Bo Liu, Sylvain Mouraret, Qiang Sun, Benjamin Salmon, Jill Helms. A WNT Protein Therapeutic improves the bone-forming capacity of autografts from aged animals. Scientific Reports. 2018, 8: 119

10. Andrew A. Smith, Jingtao Li (共同一作), Bo Liu, Daniel Hunter, Malcolm Pyles, Martin Gillette, Girijia Dhamdhere, Abo A, Anthony Oro, Jill A. Helms. Activating Hair Follicle Stem Cells via R-spondin2 to Stimulate Hair Growth. J Invest Dermatol. 2016 Aug;136(8):1549-58.

11. Xing Yin, Jingtao Li (共同一作), Jill A. Helms. Response to Letter to the Editor, "Wnt Signaling and Its Contribution to Craniofacial Tissue Homeostasis". Journal of Dental Research. 2016 Mar;95(3):357.

12. Xing Yin, Jingtao Li (共同一作), Tao Chen, Syvian Mouraret, Girija Dhamdhere , John B. Brunski, Shujuan Zou, Jill A. Helms. Rescuing failed oral implant via Wnt activation. Journal of Clinical Periodontology. 2016 Feb;43(2):180-92

13. Xing Yin, Jingtao Li (共同一作), Benjamin Salmon, Lan Huang L, Lim WH, Bo Liu, Daniel J. Hunter, Chase C. Ransom. Gurpreet Singh, Sujuan Zou, Jill A. Helms. Wnt Signaling and its contribution to craniofacial tissue. Journal of Dental Research. 2015, 94(11): 1487-1494.

14. Bei Zhang, Chunli Guo, Heng Yin, Qian Zheng, Bing Shi, Jingtao Li(通讯作者). The Correlation Between Consonant Articulation and Velopharyngeal Function in Patients With Unoperated Submucous Cleft Palate. Journal of Craniofacial Surgery.2020.6,31(4):1070-1073.

15. href="https://www.ncbi.nlm.nih.gov/pubmed/?term=Luo%20X%5BAuthor%5D&cauthor=true&cauthor_uid=31864856" Luo X, Guo C, Yin H, Shi B, Yin X, Li J(通讯作者). Comparison between Hogan pharyngeal flap and sphincter pharyngoplasty in postoperative velopharyngeal function. British Journal of Oral Maxillofacial Surgery. 2020.April,58(4):291-295.

16. Hanyao Huang, Xu Cheng, Yang Wang, Dantong Huang, Yuhao Wei, Heng Yin, Bing Shi, Jingtao Li(通讯作者). Computational Fluid Dynamic Analysis of Different Velopharyngeal Closure Patterns. Annals of Otology, Rhinology & Laryngology.2020.129(2):157-163.

17. Yuhao Wei, Tianhang Zhong, Xing Yin, Bing Shi, Qian Zheng, and Jingtao Li(通讯作者). "Dynamic nasolabial growth after primary surgery for patients with bilateral cleft lip: a five-year follow-up study." Journal of Oral and Maxillofacial Surgery. 2019, 77(10): 2125.e1-2125.e10.

18. Xu Rui, Yuhao Wei, Xing Yin, Bing Shi, Jingtao Li(通讯作者). "miR-20a suppresses chondrogenic differentiation of ATDC5 cells by regulating Atg7." Scientific reports 2019,9(1): 9243.

19. Hanyao Huang, Xu Cheng, Yang Wang, Dantong Huang, Yuhao Wei, Heng Yin, Bing Shi, Jingtao Li(通讯作者). Analysis of Velopharyngeal Functions Using Computational Fluid Dynamics Simulations. Annals of Otology, Rhinology & Laryngology. 2019,128(8):742-748.

20. Huang, Hanyao, Xu Cheng, Xiangyou Luo, Bing Shi, Jingtao Li(通讯作者). Biomechanical analyses of common suspension sutures in primary cleft lip rhinoplasty[J]. Head & face medicine, 2019, 15(1): 20.

21. Luo X, Huang H, Yin X, Shi B, Li J(通讯作者). Functional stability analyses of maxillofacial skeleton bearing cleft deformities. Scientific reports. 2019;9: 4261.

22. Cheng Xu, Hanyao Huang, Bing Shi, Jingtao Li(通讯作者). A novel intraoral injection technique for rat levator veli palatini muscle regeneration. [J] Annals of Anatomy,2019, Feb,10(223):77-84.

23. Cheng, X., Song, L., Lan, M., Shi, B., & Li, J(通讯作者). Morphological and molecular comparisons between tibialis anterior muscle and levator veli palatini muscle: a preliminary study on their augmentation potential. Experimental & Therapeutic Medicine, 2018, 15(1), 247-253.

24. Hanyao Huang, Yeping Li, Xiangyou Luo, Xu Cheng, Bing Shi, Jingtao Li(通讯作者). Mechanical analyses of critical surgical maneuvers in the correction of cleft lip nasal deformity. PLoS One, 2018,3(4): e0195583.

25. Hanyao Huang, Xiangyou Luo, Xu Cheng, Bing Shi, Jingtao Li(通讯作者). Biomechanical simulation of correcting primary unilateral cleft lip nasal deformity. PLoS ONE 2018, 13(6): e0199964.

26. Xu Cheng, Hanyao Huang, Xiangyou Luo, Bing Shi, Jingtao Li(通讯作者). Wnt7a induces satellite cell expansion, myofiber hyperplasia and hypertrophy in rat craniofacial muscle. Scientific Reports. 2018, 8: 10613.

27. Huang, H., Luo, X., Cheng, X., Zhang, Z., Ma, G., Shi, B., & Li, J(通讯作者). Recapitulation of Unilateral Cleft Lip Nasal Deformity on Normal Nasal Structure: A Finite Element Model Analysis. Journal of craniofacial surgery. 2018, 29 (8):1

28. Congcong Cao, Xue Xu, Bing Shi, QIan Zheng, Jingtao Li(通讯作者). Is cleft severity correlated with intrinsic growth pattern? Observation from unoperated adult patients with submucous cleft palate. Journal of craniofacial surgery. 2017, 28(9):1451-1455.

29. R.Xu, N.Ye, S.Zhu, B.Shi, J.Li(共同通讯), W.Lai. Comparison of the postoperative and follow-up accuracy of articulator model surgery and virtual surgical planning in skeletal class III patients. British Journal of Oral Maxillofacial Surgery. In press, Available online 20 May 2020

30. Yin, Xing, Chenchen Zhou, Jingtao Li, Renkai Liu, Bing Shi, Quan Yuan, and Shujuan Zou. "Autophagy in bone homeostasis and the onset of osteoporosis." Bone Research 7, no. 1 (2019): 1-16.

31. Chelsey A. Johnson, Jingtao Li, Jill A Helms. Midfacial growth and surgically induced growth arrest. Plastic and Reconstructive Surgery, 2014 Oct;134(4 Suppl 1):20.

32. Wei Jing, Andrew A.Smith AA, Bo Liu, Jingtao Li, Daniel J. Hunter, Girija Dhamdhere, Benjamin Salmon, Jay Jiang, Du Cheng, Chelsey A. Johnson, Serafin Chen, Gurpreet Singh, Jill A Helms. Reengineering autologous bone grafts with the stem cell activator WNT3A. Biomaterials. 2015 Apr;47:29-40.

33. Lan Huang, Bo Liu, Jungyul Cha, Gongjie Yuan, Morgan Kelly, Gurpreet Singh, Sydnee Hyman, John B. Brunski, Jingtao Li, Jill A. Helms. Mechanoresponsive Properties of the Periodontal Ligament. Journal of Dental Research. 2016 Jan 14. pii: 0022034515626102.

34. Rui Zhang, Jingtao Li, Qian Zheng, Bing Shi, Sheng Li, Yan Wang, Xing He. Symmetry in nasolabial area of UCCL patients one year after primary lip repair with modified Millard technique. Oral Surgery Oral Medicine Oral Pathology Oral Radiology. 2012, 114(5): S11-S18.

35. Yi Xu, Jingtao Li, Shufan Zhao, Bing Shi, Qian Zheng, Yan Wang. Accuracy of a plastic facial cast fabricated with a custom tray in comparison with cone beam computed tomography. Oral Surgery Oral Medicine Oral Pathology Oral Radiology. 2014 Mar;117(3):e238-45.

36. Yi Xu, Jingtao Li, Shufan Zhao, Bing Shi, Qian Zheng, Yan Wang, LJ Lo. Four dimensional changes of nasolabial positions in unilateral cleft lip and palate. Journal of Craniofacial Surgery. 2013, 24(2):473-478.

37. Yi Xu, Jingtao Li, Bing Shi. Sufficient downward rotation of the christa philtri on the cleft side: a modified technique. Frontiers of Medicine. 2013 Dec;7(4):510-16.

38. Niansong Ye, Jingtao Li, Wenli Lai. Evaluating airway volume with CBCT. American Journal Orthodontics and Dentofacial Orthopedics. 2012, 142(3): 284.

39. Niansong Ye, Jingtao Li, Kefu Zhang, Yimin Yang, Wenli Lai, Fan Jian. Computer-aided design and computer-aided manufacture of a lingual orthodontic appliance using cone beam CT scanning technology. Journal of Clinical Orthodontics. 2011, 45(10): 553-559.

40. Xue Xu, Qian Zheng, Dawei Lu, Ning Huang, Jingtao Li, Sheng Li, Yan Wang, Bing Shi. Timing of palate repair affecting growth in complete unilateral cleft lip and palate. Journal of Craniofacial Surgery. 2012, 40(8):e358-362.

41. Niansong Ye, Fan Jian, Junjie Xue, Sheng Wang, Lina Liao, Wenya Huang, Xing Yang, Yang Zhou, Wenli Lai, Jingtao Li, Jing Wang. Accuracy of in-vitro tooth volumetric measurements from cone-beam computed tomography. American Journal Orthodontics and Dentofacial Orthopedics. 2012, 142(6): 879-87.

42. Yunji Wang, Shushu He, Lixia Yu, Jingtao Li, Song Chen. Accuracy of cone beam computed tomography on volumetric measurement of teeth: A pilot study. Orthodontics and Craniofacial Research. 2011;14(4):206-12.

43. Jiayu Shi, Han Zhou, Runyi Mao, Yi Chen, Jingtao Li, Haiying Huo. A preliminary study on the key factors contributing to the attractive lips of Chinese children. Asian Pacific Journal of Tropical Medicine. 2011: 412-420.

44. J. Shi, S. Lee, H.C. Pan, A. Mohammad, A. Lin, W. Guo, E. Chen, A. Ahn, J. Li, K. Ting, J.H. Kwak. Association of condylar bone quality with TMJ osteoarthritis. Journal of Dental Research, 2017 Jul;96(8):888-894.

45. 尹恒,黄汉尧,郭春丽,王希,石冰,李精韬(通讯作者). 5岁以下腭裂患儿术后腭咽闭合功能变化规律的研究.华西口腔医学杂志,2020,38(1):48-53.

46. 陈圣恺,毛渤淳,陈奕霖,周佳琦,毛靖宁,石冰,李精韬(通讯作者)。二维及三维摄影应用于单侧唇裂患者面部测量的精准性比较。口腔疾病防治,2020.1,28(1):41-46.

47. 刘楚娴, 李精韬(通讯作者), 郑谦, 郭春丽, 尹恒. 大龄腭裂患者术后腭咽闭合功能的影响因素分析. 华西口腔医学杂志. 2019.12;37(6):626.

48. 尹恒,郭春丽,石冰,李杨,李精韬(通讯作者)。黏膜下腭裂的腭咽闭合状态及语音表现分析。华西口腔医学杂志。2017,35(3):296-300.

49. 尹恒,郭春丽,石冰,李杨,李精韬(通讯作者)。黏膜下腭裂的形态分类与腭咽功能分析。华西口腔医学杂志。2016,34(5):488-492.

50. 李精韬, 周炼, 张浚睿, 蔡鸣, 李健。唇裂继发鼻唇畸形整复的设计思路。国际口腔医学杂志,2018,45(4):384-390.

51. 李精韬,石冰。孕妇饮酒与唇腭裂畸形发生关系的研究进展[J]。口腔颌面外科杂志,2011,21(1):59-61.

52. 李精韬,石冰。维生素A族与唇腭裂发生关系的研究进展[J]。国际口腔医学杂志,2012,39(3):346-348.

53. 谢蟪旭,朱玲,李精韬,杨圣,周黎明。黄芪多糖对人肺腺上皮SPC-A-1细胞增殖作用的研究[J]。四川生理科学杂志,2007,29(4):152-154.