姓名：李西宇

职称：研究员

所在学系：口腔基础医学系

研究生导师类别：博导

联系方式：lixiyu@scu.edu.cn

研究领域：用于颌骨精准修复的可示踪羟基磷灰石材料研究

个人简介

四川大学华西口腔医学院研究员、博导，口腔基础医学系副主任。长期从事用于颌骨精准修复的可示踪羟基磷灰石材料研究，围绕口腔颌骨缺损修复的临床挑战，系统构建了具有荧光、CT、MRI等多种示踪特性的纳米磷灰石晶体及颌骨再生修复新材料，实现了促进早期成骨、提高骨整合质量、长效抗菌和多模态示踪功能，可精确示踪材料的体内变化过程及其组织重建效果，揭示了材料-细胞、材料-组织的相互作用机制，并从微观层面调控和参与骨再生的生物过程。研究成果以一作及通讯作者发表在Science Advances、Small、Bioactive Materials、Chemical Engineering Journal等知名期刊上，获得6项中国发明专利授权。获中华口腔医学会“口腔医学青年科学家论坛”最具潜力奖，四川省杰青、天府青城计划青年科技人才等。担任中华口腔医学会材料专业委员会委员。

代表性论文/著作

1.Xiyu Li; Qin Zou*; Haifeng Chen; Wei Li*, In Vivo Changes of Nanoapatite Crystals during Bone Reconstruction and The Differences with Native Bone Apatite. Science Advances 2019, 5 (11), eaay6484.  

2.Xiyu Li; Juan Wu; Danxue Li; Qin Zou*; Yi Man; Ling Zou; Wei Li*, Pro-Osteogenesis and in Vivo Tracking Investigation of a Dental Implantation System Comprising Novel mTi Implant and HYH-Fe Particles. Bioactive Materials 2021, 6 (9), 2658-2666.  

3.Xiyu Li; Qin Zou*; Yi Man; Wei Li*, Synergistic Effects of Novel Superparamagnetic/Upconversion HA Material and Ti/Magnet Implant on Biological Performance and Long-Term In Vivo Tracking. Small 2019, 15 (31), 1901617. 

4.Wei Yang; Qin Zou; Chenxin Wang; Yuankun Ren; Rui Zhang; Mingyue Lin; Xueqi Zhang; Yu Liu; Boyang Wang; Wei Li; Li Jiang*; Xiyu Li*, Bioengineered functional scaffolds co-loaded with osteonectin and HA-internalizing osteoblasts for boosting bone regeneration. Chemical Engineering Journal 2026, 531, 174134. 

5.Xiyu Li; Qin Zou*; Jiawei Wei; Wei Li*, The Degradation Regulation of 3D Printed Scaffolds for Promotion of Osteogenesis and in Vivo Tracking. Composites Part B: Engineering 2021, 222, 109084.