姓名：冯晓东

　　职称：研究员

　　所在学系：口腔基础医学系

研究生导师类别：博导

　　联系方式：xiaodongfeng@scu.edu.cn

　　研究领域：信号通路传导，口腔疾病，肿瘤防治，G蛋白和GPCR，YAP/TAZ

个人简介

冯晓东博士是国家级高层次人才计划（青年项目）入选者，四川省“海外高层次人才引进计划”入选者，国际牙医师学院（ICD）中国区会员，现任四川大学华西口腔医（学）院/口腔疾病防治全国重点实验室研究员、博士研究生导师。先后在“美国国立卫生院-NIH”和“加州大学圣地亚哥分校-UCSD”从事基础医学科研工作近9年，在Cancer Cell, Nature Cell Biology, Molecular Cell以及Science Signaling等顶尖学术期刊上发表了多篇学术论文。2019年9月回国工作并启建课题组，团队具有优越的实验平台（口腔疾病防治全国重点实验室），和充足的实验经费（约600万）。现该团队亟须有科研理想热情的有志青年加入（博士后，硕士，博士，本科）。

代表性论著

1. Xiaodong Feng; Nadia Arang; Damiano Cosimo Rigiracciolo; Joo Sang Lee; Huwate Yeerna; Zhiyong Wang; Simone Lubrano; Ayush Kishore; Jonathan A.Pachter; Gabriele M.König; Marcello Maggiolini; Evi Kostenis; David D.Schlaepfer; Pablo Tamayo; Qianming Chen; Eytan Ruppin; J.Silvio Gutkind ; A Platform of Synthetic Lethal Gene Interaction Networks Reveals that the GNAQ Uveal Melanoma Oncogene Controls the Hippo Pathway through FAK, Cancer Cell, 2019, 35(3): 457

2. Feng, Xiaodong; Degese, Maria Sol; Iglesias-Bartolome, Ramiro; Vaque, Jose P.; Molinolo, Alfredo A.; Rodrigues, Murilo; Zaidi, M. Raza; Ksander, Bruce R.; Merlino, Glenn; Sodhi, Akrit; Chen, Qianming; Gutkind, J. Silvio; Hippo-Independent Activation of YAP by the GNAQ Uveal Melanoma Oncogene through a Trio-Regulated Rho GTPase Signaling Circuitry, Cancer Cell, 2014, 25(6): 831-845

3. Jiang, Yuchen; Li, Taiwen; Wu, Ying; Xu, Hao; Xie, Changqing; Dong, Yunmei; Zhong, Liang; Wang, Zhen; Zhao, Hang; Zhou, Yu; Li, Jing; Ji, Ning; Zeng, Xin; Feng, Xiaodong; Chen, Qianming ; GPR39 overexpression in OSCC promotes YAP-sustained malignant progression, Journal of Dental Research, 2020, 99(8): 949-958

4. Feng, Xiaodong; Jiang, Yuchen; Xie, Liang; Jiang, Lu; Li, Jing; Sun, Chongkui; Xu, Hao; Wang, Ruinan; Zhou, Min; Zhou, Yu; Dan, Hongxia; Wang, Zhiyong; Ji, Ning; Deng, Peng; Liao, Ga; Geng, Ning; Wang, Yun; Zhang, Dunfang; Lin, Yunfeng; Ye, Ling; Liang, Xinhua; Li, Longjiang; Luo, Gang; Feng, Mingye; Fang, Juan; Zeng, Xin; Wang, Zhi; Chen, Qianming ; Overexpression of proteasomal activator PA28alpha serves as a prognostic factor in oral squamous cell carcinoma., J Exp Clin Cancer Res, 2016, 35(1): 35-35

5. 冯晓东; 直接或间接靶向YAP/TAZ治疗头颈部肿瘤的策略选择, 华西口腔医学杂志(专家论坛), 2021, 39(5): 493-500