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硕导

廖金凤

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  姓名:廖金凤

  职称:研究员           

  所在学系:口腔基础医学系      

研究生导师类别:硕导

  电子邮箱:liaojinfeng.762@163.com 

  办公地址:四川省成都市人民南路三段14号华西口腔科研楼404

  研究方向:仿生支架的构建及其在骨/软骨/皮肤组织工程的研究;基于多功能纳米粒的肿瘤靶向治疗研究

  个人简介

2006.9-2010.6 四川大学华西药学院,学士 

2010.9-2015.6四川大学生物治疗国家重点实验室 博士(硕博连读) 

2015.7-2017.9 四川大学华西口腔医学院 讲师 2017.1-2019.1 香港理工大学应用生物及化学科技学系 “香江学者”博士后 2017.9-2021.9 四川大学华西口腔医学院 副教授

2021.9-至今 四川大学华西口腔医学院 研究员 以通讯作者和第一作者的身份发表在Bone Res.,Bioactive Mater.,ACS Appl. Mater. Interfaces,Theranostics,Nanoscale等国际知名SCI期刊论文40余篇,其中4篇论文入选为ESI高被引论文。荣获2016年度“香江学者”奖,四川省高级海外留学人才。带领的双创课题组荣获 2018 年“全国大学生基础医学创新论坛暨实验设计大赛”一等奖,并荣获华西口腔医学院大学生创新创业优秀指导教师等称号。

  研究领域

课题组致力于开展新型纳米材料及水凝胶复合支架在肿瘤治疗、软骨组织修复工程、骨组织修复工程方面的研究工作。构建了如双相仿生水凝胶、可愈合水凝胶、多孔微球复合水凝胶等复合支架在膝关节软骨的再生修复研究;设计的金棒复合纳米粒、磁性纳米凝胶、石墨烯水凝胶等在肿瘤光热治疗或肿瘤术后治疗的研究。目前,开展了基于纳米金棒的复合水凝胶在骨肿瘤等复杂性疾病的治疗研究。 主持国家自然科学基金面上项目2项及青年科学基金各1项,四川省科技厅项目1项,成都市科技局国际合作项目1项及四川大学创新火花项目1项等,受理中国发明专利2项,参编英文论著2本。

  论文/著作

  1. Bowen Tan, Yanting Wu, Yongzhi Wu, Kun Shi, Ruxia Han, Yiling Li, Zhiyong Qian, Jinfeng Liao*, Curcumin-microsphere/IR820 hybrid bifunctional hydrogels for in situ osteosarcoma chemo-co-thermal therapy and bone reconstruction. ACS Appl. Mater. Interfaces 2021, 13, 31542-31553.

  2. Jinfeng Liao, Kun Shi, Yanpeng Jia, Yanting Wu, Zhiyong Qian*, Gold nanorods and nanohydroxyapatite hybrid hydrogel for preventing bone tumor recurrence via postoperative photothermal therapy and bone regeneration promotion, Bioactive Mater., 2021, 6: 2221-2230.

  3. Jinfeng Liao, Ruxia Han, Yongzhi Wu, Zhiyong Qian*, Review of a new bone tumor therapy strategy based on bifunctional biomaterials. Bone Res., 2021, 9: 18.

  4. Bowen Tan; Quan Tang; Yongjin Zhong; Yali Wei; Linfeng He; Yanting Wu; Jiabao Wu; Jinfeng Liao*; Biomaterial-based strategies for maxillofacial tumour therapy and bone defect regeneration. International Journal of Oral Science 2021, 13: 9.

  5. Xu Zhang, Bowen Tan, Yanting Wu, Min Zhang, Jinfeng Liao*, A review on hydrogels with photothermal effect in wound healing and bone tissue engineering. Polymers 2021, 13, 2100.

  6. Jinfeng Liao, Taoran Tian, Sirong Shi, Xueping Xie, Quanquan Ma, Guo Li, Yunfeng Lin. The fabrication of biomimetic biphasic CAN-PAC hydrogel with a seamless interfacial layer applied in osteochondral defect repair. Bone Res. 2017, 5: 17018.(ESI高被引论文)

  7. Jinfeng Liao, Wenting Li, Jinrong Peng, Qian Yang, He Li, Yuquan Wei, Xiaoning Zhang, Zhiyong Qian. Combined cancer photothermal-chemotherapy based on doxorubicin/gold nanorod-loaded polymersomes. Theranostics 2015, 5 (4): 345-356. (ESI高被引论文)

  8. Jinfeng Liao, Yanpeng Jia, Yongzhi Wu, Kun Shi, Dawei Yang, Pei Li, Zhiyong Qian*. Physical-, chemical-, and biological-responsive nanomedicine for cancer therapy. Wires Nanomed. NanoBiotech. 2019, e1581

  9. Jinfeng Liao, Xiawei Wei, Bei Ran, Jinrong Peng, Ying Qu, Zhiyong Qian. Polymer hybrid magnetic nanocapsules encapsulating IR820 and PTX for external magnetic field-guided tumor targeting and multifunctional theranostics. Nanoscale 2017, 9: 2479-2491.

  10. Dawei Yang#, Jingyi Xiao#, Beiyu Wang, B; Lang Li, Xiangli Kong, Jinfeng Liao*. The immune reaction and degradation fate of scaffold in cartilage/bone tissue engineering. Mater. Sci. & Eng. C 2019, 104:109927.

  11. Jinfeng Liao, Yanpeng Jia, Lianghui Chen, Liangyu Zhou, Qiwen Li, Zhiyong Qian, Dechao Niu, Yongsheng, Pei Li*. Magnetic/gold core-shell hybrid particles for targeting and imaging-guided photothermal cancer therapy. J. Biomed. Nanotechnol. 2019, 15(10): 2072-2089.

  12. Qiwen Li#, Junru Wen#, JR, Chenlu Liu, Yanpeng Jia, Yongzhi Wu, Yue Shan, Zhiyong Qian, Jinfeng Liao*, Graphene-nanoparticle-based self-healing hydrogel in preventing postoperative recurrence of breast cancer. ACS Biomater. Sci. Eng. 2019, 5(2):768-779.

  13. Qiwen Li, Chenlu Liu, Junru Wen, Yongzhi Wu, Yue Shan, Jinfeng Liao*. The design, mechanism and biomedical application of self-healing hydrogels. Chinese Chem. Lett. 2017, 28: 1857-1874.

  14. Jinfeng Liao#, Yanpeng Jia#, Beiyu Wang, Kun Shi, Zhiyong Qian, Injectable hybrid, poly(?-caprolactone)-b-poly(ethylene glycol)-b-poly(?-caprolactone) porous microspheres/akginate hydrogel cross-linked by calcium gluconate crystals deposited in the pores of microspheres improved skin wound regeneration. ACS Biomater. Sci. Eng. 2018,4: 1029-1036.

  15. Yue Shan, Chaoyue Li, Yongzhi Wu, Qiwen Li, Liao, Jinfeng Liao*. Hybrid cellulose nanocrystal/alginate/gelatin scaffold with improved mechanical properties. RSC Adv. 2019, 9(40):22966-22979.

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